GENO — Preventative Health OS

GENO test kit
Confidential — Founder Draft

Preventative Health OS.

A unified platform combining testing, interpretation, protocols, and family cascade into the operating system for preventative health practitioners.

Practitioner-Led Three Modules, One Data Engine UK & International
Confidential
80%

of chronic disease is preventable. Almost none of it is being prevented.

Healthcare systems spend trillions treating conditions that could be caught earlier. Prevention stays theoretical because practitioners lack a single platform connecting genetics, biomarkers, and action.

£51B
Annual NHS spend on preventable conditions
4.2M
UK adults with undiagnosed genetic risk
Sources: WHO Global Health Observatory, 2024 • NHS England Annual Report, 2024
Barrier 1
Fragmentation

DNA test here. Blood panel there. Results arrive as PDFs, not protocols. Nothing connects to action.

Barrier 2
Complexity

Multi-omic data requires specialist interpretation. No single platform integrates all three into an actionable plan.

Barrier 3
No follow-through

Testing companies stop at the report. No protocol, no adherence tracking, no retesting cycle. Insight without action is entertainment.

Barrier 4
Practitioner bottleneck

Functional medicine practitioners are scarce and expensive. Prevention needs a platform that augments them, not replaces them.

Confidential

Four modules. One data engine.

Module 1 — Data Intake
Test & interpret

Practitioners order multi-modal testing (DNA, epigenetics, blood panels). Results return interpreted through the GENO Engine into actionable risk profiles. Consumers see a biological dashboard with longitudinal tracking.

Module 2 — Growth Engine
Map & cascade

Identify hereditary risk patterns, map the family tree, automate GDPR/HIPAA-compliant outreach to at-risk relatives. One patient becomes 3–5. The consumer becomes the distribution channel.

Module 3 — Retention Engine
Prescribe & track

Practitioners build personalised protocols. Platform tracks adherence, retesting, and outcomes over time. Protocol template marketplace. Full client lifecycle: intake, profiles, scheduling, outcome logging.

Shared Layer
Clinical intelligence engine

Aggregated anonymised outcome data. Every completed protocol-to-retest cycle generates structured data. Anonymous benchmarking across practitioners. Platform measurably better at 1,000 users than at 100.

Individually, each module scored weak on defensibility. Combined into one platform, the data flywheel jumps from 2/8 to a projected 5.7/8.
Confidential

Four forces. One window.

Force 1
Genomics at commercial scale

Genomics England and UK Biobank have normalised large-scale genomic data. Multi-omic testing costs dropped 90% in five years. A £100 epigenetics test is now commercially viable. The infrastructure exists.

Force 2
AI removes the interpretation bottleneck

LLM-class models can now synthesize multi-omic data into actionable protocols at scale. The PhD-per-patient interpretation barrier is gone. The missing layer is the structured data engine to feed it.

Force 3
NHS prevention mandate

NHS Long Term Plan explicitly targets prevention ROI. Integrated Care Systems under record budget pressure. Prevention is now a commissioning priority, not a nice-to-have. The institutional buyer is ready.

Force 4
Consumer demand at inflection

Post-COVID health consciousness plus the GLP-1 and longevity wave has shifted consumer appetite from reactive to proactive. Demand for personalised health optimisation is at an all-time high.

Confidential

A £51B problem. No full-stack player.

The preventative health market sits at the intersection of diagnostics, digital health, and clinical workflow. No single platform currently owns it end-to-end.

£51B
TAM: Annual NHS preventable condition spend
£3B+
SAM: UK practitioner-led preventative health
12K+
UK functional medicine & integrative practitioners
<1%
Patients with unified genetic + biomarker view
Why GENO sits at the centre

Every practitioner is currently stitching together 4–6 disconnected tools to run a prevention programme. GENO replaces that entire stack with one platform and adds the data layer none of them have.

The data flywheel changes the economics

At 10,000 completed protocols, GENO holds the world’s largest structured preventative outcome dataset. That dataset is licensable to pharma, insurers, and research. A revenue stream no pure SaaS competitor can replicate.

International from day one

The functional medicine practitioner model is identical in the US, EU, and Australia. UK launch validates the clinical model. International expansion is a distribution play, not a product rebuild.

Confidential

Pay because your health is measurably improving.

1
Test
DNA + Epi + Blood
2
See results
Biological dashboard
3
Share
Family cascade
4
Protocol
Personalised plan
5
Track
30/60/90 day
6
Retest
See improvement
7
Subscribe
Stay & compound
Loop 1 — Retention
The retest cycle

Visible improvement at every retest drives organic subscription retention. Without outcomes tracking proving the protocol works, there is no reason to retest. This loop drives subscription revenue and generates longitudinal data.

Loop 2 — Acquisition
The family cascade

One patient becomes 3–5. When hereditary risk is flagged, the consumer invites family directly. Trust-based distribution converts at >40% vs industry baseline ~30%. No ad spend required.

Loop 3 — Moat
The data feedback loop

Outcomes data refines interpretation, which improves protocols, which attracts more practitioners, which generates more data. No single competitor can replicate the full loop without starting from scratch.

Confidential

Already in motion. Not a concept.

50+
Paying customers
3
Strategic partners
£552
Entry tier live
Active
Vitality discussions
“This is the first programme that actually connects what my tests say to what I should do about it. I’ve done genetic tests before — they sat in a drawer.”
Early customer • London
“The family cascade is what got me. I tested, flagged a hereditary risk, and my sister caught something early because of it. You can’t put a price on that.”
Early customer • Family cascade
“We are exploring how GENO’s prevention data could fit into our wellness rewards model. The longitudinal outcome data is what makes this different.”
Partner discussion • Insurance
SKAI Health — Strategic Partner
THERME GROUP — Wellness Integration
Vitality — In Discussion
SEIS / EIS Eligible
Confidential

Three-sided revenue from one data engine.

Side 1
Practitioner revenue
  • SaaS subscription for workflow tools
  • Tiered pricing based on patient volume
  • Entry tier priced to maximise practitioner count (data compounds)
  • Premium tier: marketplace access & benchmarking
Side 2
Consumer revenue
  • Per-test fees (~£552 blended entry)
  • Health management subscription
  • Own-brand supplement purchases
  • Retest revenue (90-day cycles)
Side 3
Payer revenue
  • Population health data & outcomes reporting
  • “We can prove biological age decreased by X over 12 months”
  • Anonymised prescribing data licensable to pharma
  • Unlocks at 12–18 months post-launch
Confidential

£552 entry. 55% contribution margin.

Per-consumer unit economics for the standard entry tier.

£552
Entry price
-£100
Epigenetics (TruDiag)
-£65
Blood panels
-£46
DNA kit
-£35
Logistics & packaging
£306
Contribution margin

LTV compounds with subscriptions

55%
Entry margin
80%+
Subscription margin (Yr 2+)
£240
Annual subscription
£600
Annual supplements (est.)
3-year LTV per consumer

£2.4K
Entry £552 + subscriptions £720 + supplements £1,200 + retesting. The cascade multiplier (1→3–5) means effective CAC drops to £0 for family referrals. Margins improve 15–25% at volume.

Confidential

No one occupies the full quadrant.

PRACTITIONER-LED ↑
Diagnostics + Action
GENO • Preventative Health OS
No direct competitor occupies this quadrant
Diagnostics Only
Randox Health
Medichecks
Fagron Genomics
TruDiagnostic
Consumer + Action
ZOE
InsideTracker
Viome
Consumer DTC
Thriva
Muhdo
Oura / WHOOP
DIAGNOSTICS ONLY ←           → DIAGNOSTICS + ACTION

Defensibility: 2/8 → 5.7/8

Moat
Solo
Combined
Strategy
Data
0.5
0.9
Structured 30/60/90-day outcomes. First to 10K+ protocols wins permanently.
Network effects
0
0.8
Anonymous benchmarking. Measurably better at scale. Architected in before launch.
Workflow
0.5
0.8
Full client lifecycle: intake, profiles, protocols, scheduling, outcome logging.
Distribution
0.5
0.8
IFM curriculum embedding. Exclusive partner deals. Supplement transaction layer.
Total
2.0/8
5.7/8
Defensible and compounding.
Confidential

Why us.

The team that can execute this must combine clinical credibility, data architecture, and commercial distribution.

Founder
[Founder Name]

[Role, background, relevant expertise. Why this person can build and sell this product.]

Co-Founder / CTO
[Co-Founder Name]

[Role, background, technical credentials. Why this person can architect the data engine.]

Clinical Lead
[Clinical Advisor Name]

[Clinical credentials, practitioner network, relevant publications or regulatory experience.]

Confidential

Raising £500K. Pre-seed. £5M post-money.

£500K
Raise (floor). 12.5% dilution at £4M post-money.
12–15mo
Runway. Lean team of 3–4, outsourced engineering.
£15M+
Seed valuation target at month 12–15 on milestones.

Milestones this raise funds

  • 30–50 practitioners onboarded on Module 1 (Test & Interpret)
  • 200+ consumers with structured 30/60/90-day outcome data
  • Family cascade demonstrated: 1 patient producing 2–3+ referrals
  • Revenue trajectory: £30K–50K/month run rate by month 12
  • At least one strategic partnership formalised (Vitality or equivalent)

Hitting these numbers supports a seed raise at £3–5M on a £15–20M valuation. Payer revenue and Modules 2 & 3 are seed territory.

Use of funds (£500K)

40%
Product & Engineering
£200K. Platform build, GENO Engine, data schema, one senior engineer hire.
30%
Growth & Partnerships
£150K. Practitioner acquisition, IFM embedding, lab partnerships, initial marketing.
20%
Operations & Regulatory
£100K. 3PL setup, SOC 2 prep, GDPR health data compliance, legal, insurance.
10%
Buffer
£50K. Contingency, unexpected costs, early compliance overshoot.
SEIS first £250K — 50% income tax relief
EIS remainder — 30% relief + CGT exemption